Cell-Based Screen Using Amyloid Mimic β23 Expression Identifies Peucedanocoumarin III as a Novel Inhibitor of α-Synuclein and Huntingtin Aggregates

Aggregates of disease-causing proteins dysregulate cellular functions, thereby causing neuronal cell loss in diverse neurodegenerative diseases. Although many in vitro or in vivo studies of protein aggregate inhibitors have been performed, a therapeutic strategy to control aggregate toxicity has not...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Mol Cells
Autors principals: Ham, Sangwoo, Kim, Hyojung, Hwang, Seojin, Kang, Hyunook, Yun, Seung Pil, Kim, Sangjune, Kim, Donghoon, Kwon, Hyun Sook, Lee, Yun-Song, Cho, MyoungLae, Shin, Heung-Mook, Choi, Heejung, Chung, Ka Young, Ko, Han Seok, Lee, Gum Hwa, Lee, Yunjong
Format: Artigo
Idioma:Inglês
Publicat: Korean Society for Molecular and Cellular Biology 2019
Matèries:
Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6602149/
https://ncbi.nlm.nih.gov/pubmed/31250621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14348/molcells.2019.0091
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars