Estrogen receptor activation contributes to RNF146 expression and neuroprotection in Parkinson's disease models

RNF146 is an E3 ubiquitin ligase that specifically recognizes and polyubiquitinates poly (ADP-ribose) (PAR)-conjugated substrates for proteasomal degradation. RNF146 has been shown to be neuroprotective against PAR polymerase-1 (PARP1)-induced cell death during stroke. Here we report that RNF146 exp...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Kim, Hyojung, Ham, Sangwoo, Lee, Joon Yeop, Jo, Areum, Lee, Gum Hwa, Lee, Yun-Song, Cho, MyoungLae, Shin, Heung-Mook, Kim, Donghoon, Pletnikova, Olga, Troncoso, Juan C., Shin, Joo-Ho, Lee, Yun-Il, Lee, Yunjong
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5739769/
https://ncbi.nlm.nih.gov/pubmed/29290984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21828
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