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Estrogen receptor activation contributes to RNF146 expression and neuroprotection in Parkinson's disease models
RNF146 is an E3 ubiquitin ligase that specifically recognizes and polyubiquitinates poly (ADP-ribose) (PAR)-conjugated substrates for proteasomal degradation. RNF146 has been shown to be neuroprotective against PAR polymerase-1 (PARP1)-induced cell death during stroke. Here we report that RNF146 exp...
שמור ב:
| הוצא לאור ב: | Oncotarget |
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| Main Authors: | , , , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Impact Journals LLC
2017
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5739769/ https://ncbi.nlm.nih.gov/pubmed/29290984 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21828 |
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