RheoScale: A Tool to Aggregate and Quantify Experimentally-Determined Substitution Outcomes for Multiple Variants at Individual Protein Positions

Human mutations often cause amino acid changes (variants) that can alter protein function or stability. Some variants fall at protein positions that experimentally exhibit “rheostatic” mutation outcomes (different amino acid substitutions lead to a range of functional outcomes). In ongoing studies o...

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Detaylı Bibliyografya
Yayımlandı:Hum Mutat
Asıl Yazarlar: Hodges, Abby M., Fenton, Aron W., Dougherty, Larissa L., Overholt, Andrew C., Swint-Kruse, Liskin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6602090/
https://ncbi.nlm.nih.gov/pubmed/30117637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/humu.23616
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