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Using Evolution to Guide Protein Engineering: The Devil IS in the Details
For decades, protein engineers have endeavored to reengineer existing proteins for novel applications. Overall, protein folds and gross functions can be readily transferred from one protein to another by transplanting large blocks of sequence (i.e., domain recombination). However, predictably fine-t...
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| Publicado no: | Biophys J |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4945580/ https://ncbi.nlm.nih.gov/pubmed/27410729 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.05.030 |
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