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Using Evolution to Guide Protein Engineering: The Devil IS in the Details
For decades, protein engineers have endeavored to reengineer existing proteins for novel applications. Overall, protein folds and gross functions can be readily transferred from one protein to another by transplanting large blocks of sequence (i.e., domain recombination). However, predictably fine-t...
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| Udgivet i: | Biophys J |
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| Hovedforfatter: | |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Biophysical Society
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4945580/ https://ncbi.nlm.nih.gov/pubmed/27410729 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.05.030 |
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