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RheoScale: A Tool to Aggregate and Quantify Experimentally-Determined Substitution Outcomes for Multiple Variants at Individual Protein Positions
Human mutations often cause amino acid changes (variants) that can alter protein function or stability. Some variants fall at protein positions that experimentally exhibit “rheostatic” mutation outcomes (different amino acid substitutions lead to a range of functional outcomes). In ongoing studies o...
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| Опубликовано в: : | Hum Mutat |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6602090/ https://ncbi.nlm.nih.gov/pubmed/30117637 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/humu.23616 |
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