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The strengths and limitations of using biolayer interferometry to monitor equilibrium titrations of biomolecules

Every method used to quantify biomolecular interactions has its own strengths and limitations. To quantify protein‐DNA binding affinities, nitrocellulose filter binding assays with (32)P‐labeled DNA quantify K (d) values from 10(−12) to 10(−8) M but have several technical limitations. Here, we consi...

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Detaylı Bibliyografya
Yayımlandı:Protein Sci
Asıl Yazarlar: Weeramange, Chamitha J., Fairlamb, Max S., Singh, Dipika, Fenton, Aron W., Swint‐Kruse, Liskin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley & Sons, Inc. 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7096710/
https://ncbi.nlm.nih.gov/pubmed/31943488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3827
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