Cerebellar Shank2 Regulates Excitatory Synapse Density, Motor Coordination, and Specific Repetitive and Anxiety-Like Behaviors

Shank2 is a multidomain scaffolding protein implicated in the structural and functional coordination of multiprotein complexes at excitatory postsynaptic sites as well as in psychiatric disorders, including autism spectrum disorders. While Shank2 is strongly expressed in the cerebellum, whether Shan...

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Gepubliceerd in:J Neurosci
Hoofdauteurs: Ha, Seungmin, Lee, Dongwon, Cho, Yi Sul, Chung, Changuk, Yoo, Ye-Eun, Kim, Jihye, Lee, Jiseok, Kim, Woohyun, Kim, Hyosang, Bae, Yong Chul, Tanaka-Yamamoto, Keiko, Kim, Eunjoon
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Society for Neuroscience 2016
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Research Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6601982/
https://ncbi.nlm.nih.gov/pubmed/27903723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1849-16.2016
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