Φορτώνει......
Reversal of Pathologic Lipid Accumulation in NPC1-Deficient Neurons by Drug-Promoted Release of LAMP1-Coated Lamellar Inclusions
Aging and pathologic conditions cause intracellular aggregation of macromolecules and the dysfunction and degeneration of neurons, but the mechanisms are largely unknown. Prime examples are lysosomal storage disorders such as Niemann–Pick type C (NPC) disease, where defects in the endosomal–lysosoma...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | J Neurosci |
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| Κύριοι συγγραφείς: | , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Society for Neuroscience
2016
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6601882/ https://ncbi.nlm.nih.gov/pubmed/27466344 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0900-16.2016 |
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