लोड हो रहा है...
Cholesterol Accumulation Is Associated with Lysosomal Dysfunction and Autophagic Stress in Npc1(−/−) Mouse Brain
Niemann-Pick type C (NPC) disease is an autosomal recessive disorder caused by mutations of NPC1 and NPC2 genes. Progressive neurodegeneration that accompanies NPC is fatal, but the underlying mechanisms are still poorly understood. In the present study, we characterized the association of autophagi...
में बचाया:
| मुख्य लेखकों: | , , , , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
American Society for Investigative Pathology
2007
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1959498/ https://ncbi.nlm.nih.gov/pubmed/17631520 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.070052 |
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