Attenuated glutamine synthetase as a selection marker in CHO cells to efficiently isolate highly productive stable cells for the production of antibodies and other biologics

Chinese hamster ovary (CHO) cells are the biopharmaceutical industry’s primary means of manufacturing therapeutic proteins, including monoclonal antibodies. The major challenge in cell line development for the production of recombinant biopharmaceuticals lies in generating and isolating rare high-pr...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:MAbs
Egile Nagusiak: Lin, Pao-Chun, Chan, Kah Fai, Kiess, Irene A., Tan, Joselyn, Shahreel, Wahyu, Wong, Sze-Yue, Song, Zhiwei
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Taylor & Francis 2019
Gaiak:
Report
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6601560/
https://ncbi.nlm.nih.gov/pubmed/31043114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2019.1612690
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