Endothelial cell Piezo1 mediates pressure-induced lung vascular hyperpermeability via disruption of adherens junctions

Increased pulmonary microvessel pressure experienced in left heart failure, head trauma, or high altitude can lead to endothelial barrier disruption referred to as capillary “stress failure” that causes leakage of protein-rich plasma and pulmonary edema. However, little is known about vascular endot...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Friedrich, Emily E., Hong, Zhigang, Xiong, Shiqin, Zhong, Ming, Di, Anke, Rehman, Jalees, Komarova, Yulia A., Malik, Asrar B.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2019
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6600969/
https://ncbi.nlm.nih.gov/pubmed/31186359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1902165116
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