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Endothelial cell Piezo1 mediates pressure-induced lung vascular hyperpermeability via disruption of adherens junctions

Increased pulmonary microvessel pressure experienced in left heart failure, head trauma, or high altitude can lead to endothelial barrier disruption referred to as capillary “stress failure” that causes leakage of protein-rich plasma and pulmonary edema. However, little is known about vascular endot...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Proc Natl Acad Sci U S A
Main Authors: Friedrich, Emily E., Hong, Zhigang, Xiong, Shiqin, Zhong, Ming, Di, Anke, Rehman, Jalees, Komarova, Yulia A., Malik, Asrar B.
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2019
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6600969/
https://ncbi.nlm.nih.gov/pubmed/31186359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1902165116
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