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Alveolar Stretch Activation of Endothelial Piezo1 Protects Adherens Junctions and Lung Vascular Barrier
Disruption of alveolar–capillary barriers is a major complication of high-volume mechanical ventilation referred to as “ventilator-induced lung injury.” The stretching force in alveoli is transmitted to endothelial cells, increasing the tension on underlying endothelial plasma membrane. The mechanos...
Enregistré dans:
| Publié dans: | Am J Respir Cell Mol Biol |
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| Auteurs principaux: | , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Thoracic Society
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6993544/ https://ncbi.nlm.nih.gov/pubmed/31409093 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2019-0024OC |
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