Endothelial cell Piezo1 mediates pressure-induced lung vascular hyperpermeability via disruption of adherens junctions

Increased pulmonary microvessel pressure experienced in left heart failure, head trauma, or high altitude can lead to endothelial barrier disruption referred to as capillary “stress failure” that causes leakage of protein-rich plasma and pulmonary edema. However, little is known about vascular endot...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Friedrich, Emily E., Hong, Zhigang, Xiong, Shiqin, Zhong, Ming, Di, Anke, Rehman, Jalees, Komarova, Yulia A., Malik, Asrar B.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2019
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6600969/
https://ncbi.nlm.nih.gov/pubmed/31186359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1902165116
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