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Decreased synthesis of ribosomal proteins in tauopathy revealed by non‐canonical amino acid labelling

Tau is a scaffolding protein that serves multiple cellular functions that are perturbed in neurodegenerative diseases, including Alzheimer's disease (AD) and frontotemporal dementia (FTD). We have recently shown that amyloid‐β, the second hallmark of AD, induces de novo protein synthesis of tau...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:EMBO J
Prif Awduron: Evans, Harrison Tudor, Benetatos, Joseph, van Roijen, Marloes, Bodea, Liviu‐Gabriel, Götz, Jürgen
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6600635/
https://ncbi.nlm.nih.gov/pubmed/31268600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2018101174
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