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Non-canonical amino acid labeling in proteomics and biotechnology

Metabolic labeling of proteins with non-canonical amino acids (ncAAs) provides unique bioorthogonal chemical groups during de novo synthesis by taking advantage of both endogenous and heterologous protein synthesis machineries. Labeled proteins can then be selectively conjugated to fluorophores, aff...

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Bibliografske podrobnosti
izdano v:J Biol Eng
Main Authors: Saleh, Aya M., Wilding, Kristen M., Calve, Sarah, Bundy, Bradley C., Kinzer-Ursem, Tamara L.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6529998/
https://ncbi.nlm.nih.gov/pubmed/31139251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13036-019-0166-3
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