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Non-canonical amino acid labeling in proteomics and biotechnology

Metabolic labeling of proteins with non-canonical amino acids (ncAAs) provides unique bioorthogonal chemical groups during de novo synthesis by taking advantage of both endogenous and heterologous protein synthesis machineries. Labeled proteins can then be selectively conjugated to fluorophores, aff...

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Bibliographic Details
Published in:J Biol Eng
Main Authors: Saleh, Aya M., Wilding, Kristen M., Calve, Sarah, Bundy, Bradley C., Kinzer-Ursem, Tamara L.
Format: Artigo
Language:Inglês
Published: BioMed Central 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6529998/
https://ncbi.nlm.nih.gov/pubmed/31139251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13036-019-0166-3
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