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Light-Activated Proteomic Labeling via Photocaged Bioorthogonal Non-Canonical Amino Acids
This work introduces light-activated bioorthogonal non-canonical amino acid tagging (laBONCAT) as a method to selectively label, isolate, and identify proteins newly synthesized at user-defined regions in tissue culture. By photocaging L-azidohomoalanine (Aha), metabolic incorporation into proteins...
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| Publicado no: | ACS Chem Biol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5856642/ https://ncbi.nlm.nih.gov/pubmed/29419281 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.7b01023 |
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