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Decreased synthesis of ribosomal proteins in tauopathy revealed by non‐canonical amino acid labelling

Tau is a scaffolding protein that serves multiple cellular functions that are perturbed in neurodegenerative diseases, including Alzheimer's disease (AD) and frontotemporal dementia (FTD). We have recently shown that amyloid‐β, the second hallmark of AD, induces de novo protein synthesis of tau...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Evans, Harrison Tudor, Benetatos, Joseph, van Roijen, Marloes, Bodea, Liviu‐Gabriel, Götz, Jürgen
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6600635/
https://ncbi.nlm.nih.gov/pubmed/31268600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2018101174
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