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Interference with Amyloid-β Nucleation by Transient Ligand Interaction
Amyloid-β peptide (Aβ) is an intrinsically disordered protein (IDP) associated with Alzheimer’s disease. The structural flexibility and aggregation propensity of Aβ pose major challenges for elucidating the interaction between Aβ monomers and ligands. All-D-peptides consisting solely of D-enantiomer...
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| Publicado no: | Molecules |
|---|---|
| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6600523/ https://ncbi.nlm.nih.gov/pubmed/31195746 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24112129 |
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