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Piceatannol attenuates RANKL-induced osteoclast differentiation and bone resorption by suppressing MAPK, NF-κB and AKT signalling pathways and promotes Caspase3-mediated apoptosis of mature osteoclasts

Osteoclasts are multinuclear giant cells that have unique ability to degrade bone. The search for new medicines that modulate the formation and function of osteoclasts is a potential approach for treating osteoclast-related bone diseases. Piceatannol (PIC) is a natural organic polyphenolic stilbene...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:R Soc Open Sci
Egile Nagusiak: Yan, Liuliu, Lu, Lulu, Hu, Fangbin, Shetti, Dattatrya, Wei, Kun
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Royal Society 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6599799/
https://ncbi.nlm.nih.gov/pubmed/31312498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsos.190360
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