The role of Na(v)1.7 and methylglyoxal-mediated activation of TRPA1 in itch and hypoalgesia in a murine model of type 1 diabetes

Methylglyoxal (MGO), an endogenous reactive carbonyl compound, plays a key role in the pathogenesis of diabetic neuropathy. The aim of this study is to investigate the role of MGO in diabetic itch and hypoalgesia, two common symptoms associated with diabetic neuropathy. Methods: Scratching behavior,...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Cheng, Ruo-Xiao, Feng, Yu, Liu, Di, Wang, Zhi-Hong, Zhang, Jiang-Tao, Chen, Li-Hua, Su, Cun-Jin, Wang, Bing, Huang, Ya, Ji, Ru-Rong, Hu, Ji, Liu, Tong
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6599654/
https://ncbi.nlm.nih.gov/pubmed/31285762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.36077
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados