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Cellular Membrane Fluidity in Amyloid Precursor Protein Processing
The senile plaque is a pathologic hallmark of Alzheimer’s disease (AD). Amyloid-β peptide (Aβ), the main constituent of senile plaques, is neurotoxic especially in its oligomeric form. Aβ is derived from the sequential cleavage of amyloid precursor protein (APP) by β- and γ-secretases in the amyloid...
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| Publicado en: | Mol Neurobiol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6599628/ https://ncbi.nlm.nih.gov/pubmed/24553856 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-014-8652-6 |
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