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Impacts of Membrane Biophysics in Alzheimer's Disease: From Amyloid Precursor Protein Processing to Aβ Peptide-Induced Membrane Changes

An increasing amount of evidence supports the notion that cytotoxic effects of amyloid-β peptide (Aβ), the main constituent of senile plaques in Alzheimer's disease (AD), are strongly associated with its ability to interact with membranes of neurons and other cerebral cells. Aβ is derived from...

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Autors principals: Askarova, Sholpan, Yang, Xiaoguang, Lee, James C.-M.
Format: Artigo
Idioma:Inglês
Publicat: SAGE-Hindawi Access to Research 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3087431/
https://ncbi.nlm.nih.gov/pubmed/21547213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2011/134971
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