High-resolution characterization of allelic and haplotypic HLA frequency distribution in a Spanish population using high-throughput next-generation sequencing

Next-generation sequencing (NGS) at the HLA-A, -B, -C, -DPA1, -DPB1, -DQA1, -DQB1, -DRB1 and -DRB¾/5 loci was performed on 282 healthy unrelated individuals from different major regions of Spain. High-resolution HLA genotypes defined by full sequencing of class I loci and extended coverage of class...

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Publicado no:Hum Immunol
Main Authors: Montero-Martín, Gonzalo, Mallempati, Kalyan C., Gangavarapu, Sridevi, Sánchez-Gordo, Francisco, Herrero-Mata, Maria J., Balas, Antonio, Vicario, Jose L., Sánchez-García, Florentino, González-Escribano, Maria F., Muro, Manuel, Moya-Quiles, Maria R., González-Fernández, Rafael, Ocejo-Vinyals, Javier G., Marín, Luis, Creary, Lisa E., Osoegawa, Kazutoyo, Vayntrub, Tamara, Caro-Oleas, Jose L., Vilches, Carlos, Planelles, Dolores, Fernández-Viña, Marcelo A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6599556/
https://ncbi.nlm.nih.gov/pubmed/30763600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.humimm.2019.02.005
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