In vitro genotoxicity of nitroimidazoles as a tool in the search of new trypanocidal agents

BACKGROUND: Only benznidazole (Bnz) (1) and nifurtimox (Nfx) (2) are licensed for the treatment of Chagas disease although their safety and efficacy profile are far from ideal. Farmanguinhos from Fiocruz has developed seven nitroimidazole compounds (4-10) analogs of megazol (3). OBJECTIVES: To evalu...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Mem Inst Oswaldo Cruz
Autors principals: Von Trompowsky, Ana Claudia Manoel, Conde, Taline Ramos, Lemos, Renata Calil, Quaresma, Bruna Maria CS, Pitombeira, Marcelly Cristina SR, de Carvalho, Alcione Silva, Boechat, Núbia, Salomão, Kelly, de Castro, Solange Lisboa, Zamith, Helena Pereira da Silva
Format: Artigo
Idioma:Inglês
Publicat: Instituto Oswaldo Cruz, Ministério da Saúde 2019
Matèries:
Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6598759/
https://ncbi.nlm.nih.gov/pubmed/31271593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/0074-02760190017
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars