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The endonuclease Cue2 cleaves mRNAs at stalled ribosomes during No Go Decay
Translation of problematic sequences in mRNAs leads to ribosome collisions that trigger a series of quality control events including ribosome rescue, degradation of the stalled nascent polypeptide, and targeting of the mRNA for decay (No Go Decay or NGD). Using a reverse genetic screen in yeast, we...
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| Publicado no: | eLife |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6598757/ https://ncbi.nlm.nih.gov/pubmed/31219035 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.49117 |
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