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Ribosome collision is critical for quality control during no-go decay

No-go decay (NGD) is a eukaryotic quality control mechanism that evolved to cope with translational arrests. The process is characterized by an endonucleolytic cleavage near the stall sequence, but the mechanistic details are unclear. Our analysis of cleavage sites indicates that cleavage requires m...

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Detalles Bibliográficos
Publicado en:Mol Cell
Main Authors: Simms, Carrie L., Yan, Liewei L., Zaher, Hani S.
Formato: Artigo
Idioma:Inglês
Publicado: 2017
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5659757/
https://ncbi.nlm.nih.gov/pubmed/28943311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2017.08.019
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