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Ribosome Collisions Result in +1 Frameshifting in the Absence of No-Go Decay

During translation, an mRNA is typically occupied by multiple ribosomes sparsely distributed across the coding sequence. This distribution, mediated by slow rates of initiation relative to elongation, ensures that they rarely collide with each other, but given the stochastic nature of protein synthe...

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Podrobná bibliografie
Vydáno v:Cell Rep
Hlavní autoři: Simms, Carrie L., Yan, Liewei L., Qiu, Jessica K., Zaher, Hani S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6701860/
https://ncbi.nlm.nih.gov/pubmed/31412239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.07.046
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