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Cisplatin protects mice from challenge of Cryptococcus neoformans by targeting the Prp8 intein

The Prp8 intein is one of the most widespread eukaryotic inteins, present in important pathogenic fungi, including Cryptococcus and Aspergillus species. Because the processed Prp8 carries out essential and non-redundant cellular functions, a Prp8 intein inhibitor is a mechanistically novel antifunga...

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Detalhes bibliográficos
Publicado no:Emerg Microbes Infect
Main Authors: Li, Zhong, Fu, Bin, Green, Cathleen M., Liu, Binbin, Zhang, Jing, Lang, Yuekun, Chaturvedi, Sudha, Belfort, Marlene, Liao, Guojian, Li, Hongmin
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6598491/
https://ncbi.nlm.nih.gov/pubmed/31223062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/22221751.2019.1625727
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