Spliceosomal Prp8 intein at the crossroads of protein and RNA splicing

The spliceosome is a large ribonucleoprotein complex that removes introns from pre-mRNAs. At its functional core lies the essential pre-mRNA processing factor 8 (Prp8) protein. Across diverse eukaryotes, this protein cofactor of RNA catalysis harbors a self-splicing element called an intein. Inteins...

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Gepubliceerd in:PLoS Biol
Hoofdauteurs: Green, Cathleen M., Li, Zhong, Smith, Aaron D., Novikova, Olga, Bacot-Davis, Valjean R., Gao, Fengshan, Hu, Saiyang, Banavali, Nilesh K., Thiele, Dennis J., Li, Hongmin, Belfort, Marlene
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2019
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6805012/
https://ncbi.nlm.nih.gov/pubmed/31600193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000104
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