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Exploring Intein Inhibition by Platinum Compounds as an Antimicrobial Strategy
Inteins, self-splicing protein elements, interrupt genes and proteins in many microbes, including the human pathogen Mycobacterium tuberculosis. Using conserved catalytic nucleophiles at their N- and C-terminal splice junctions, inteins are able to excise out of precursor polypeptides. The splicing...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5077202/ https://ncbi.nlm.nih.gov/pubmed/27609519 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.747824 |
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