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E46K-like α-synuclein mutants increase lipid interactions and disrupt membrane selectivity
Parkinson's disease (PD) is one of the most common neurodegenerative disorders, and both genetic and histopathological evidence have implicated the ubiquitous presynaptic protein α-synuclein (αSyn) in its pathogenesis. Recent work has investigated how disrupting αSyn's interaction with mem...
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| Publicado no: | J Biol Chem |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6597829/ https://ncbi.nlm.nih.gov/pubmed/31048377 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006551 |
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