Smoothened-dependent and -independent pathways in mammalian noncanonical Hedgehog signaling

Hedgehog proteins are pivotal morphogens acting through a canonical pathway involving first activation of ligand binding to Patched followed by alleviation of Smoothened receptor inhibition, leading to activation of Gli transcription factors. Noncanonical Hedgehog signaling remains poorly characteri...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Biol Chem
Prif Awduron: Faria, Alessandra V. de S., Akyala, Adamu Ishaku, Parikh, Kaushal, Brüggemann, Lois W., Spek, C. Arnold, Cao, Wanlu, Bruno, Marco J., Bijlsma, Maarten F., Fuhler, Gwenny M., Peppelenbosch, Maikel P.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2019
Pynciau:
Signal Transduction
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6597826/
https://ncbi.nlm.nih.gov/pubmed/30992365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.007956
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg