FGFR4 overexpression and hotspot mutations in metastatic ER+ breast cancer are enriched in the lobular subtype

Invasive lobular carcinoma (ILC) is an understudied subtype of breast cancer that requires novel therapies in the advanced setting. To study acquired resistance to endocrine therapy in ILC, we have recently performed RNA-Sequencing on long-term estrogen deprived cell lines and identified FGFR4 overe...

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Bibliografske podrobnosti
izdano v:NPJ Breast Cancer
Main Authors: Levine, Kevin M., Priedigkeit, Nolan, Basudan, Ahmed, Tasdemir, Nilgun, Sikora, Matthew J., Sokol, Ethan S., Hartmaier, Ryan J., Ding, Kai, Ahmad, Nedah Z., Watters, Rebecca J., Weiss, Kurt R., Blohmer, Jens-Uwe, Denkert, Carsten, Machleidt, Anna, Karsten, Maria M., Boisen, Michelle M., Elishaev, Esther, Lucas, Peter C., Lee, Adrian V., Oesterreich, Steffi
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Brief Communication
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6597581/
https://ncbi.nlm.nih.gov/pubmed/31263748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41523-019-0114-x
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