Key regulators of lipid metabolism drive endocrine resistance in invasive lobular breast cancer

BACKGROUND: Invasive lobular breast carcinoma (ILC) is a histological subtype of breast cancer that is characterized by loss of E-cadherin and high expression of estrogen receptor alpha (ERα). In many cases, ILC is effectively treated with adjuvant aromatase inhibitors (AIs); however, acquired AI re...

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Vydáno v:Breast Cancer Res
Hlavní autoři: Du, Tian, Sikora, Matthew J., Levine, Kevin M., Tasdemir, Nilgun, Riggins, Rebecca B., Wendell, Stacy G., Van Houten, Bennett, Oesterreich, Steffi
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6124012/
https://ncbi.nlm.nih.gov/pubmed/30180878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-018-1041-8
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