FGFR4 overexpression and hotspot mutations in metastatic ER+ breast cancer are enriched in the lobular subtype

Invasive lobular carcinoma (ILC) is an understudied subtype of breast cancer that requires novel therapies in the advanced setting. To study acquired resistance to endocrine therapy in ILC, we have recently performed RNA-Sequencing on long-term estrogen deprived cell lines and identified FGFR4 overe...

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Библиографические подробности
Опубликовано в: :NPJ Breast Cancer
Главные авторы: Levine, Kevin M., Priedigkeit, Nolan, Basudan, Ahmed, Tasdemir, Nilgun, Sikora, Matthew J., Sokol, Ethan S., Hartmaier, Ryan J., Ding, Kai, Ahmad, Nedah Z., Watters, Rebecca J., Weiss, Kurt R., Blohmer, Jens-Uwe, Denkert, Carsten, Machleidt, Anna, Karsten, Maria M., Boisen, Michelle M., Elishaev, Esther, Lucas, Peter C., Lee, Adrian V., Oesterreich, Steffi
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2019
Предметы:
Brief Communication
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6597581/
https://ncbi.nlm.nih.gov/pubmed/31263748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41523-019-0114-x
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