Frequent ESR1 and CDK Pathway Copy Number Alterations in Metastatic Breast Cancer

DNA sequencing has identified a limited number of driver mutations in metastatic breast cancer beyond single base-pair mutations in the estrogen receptor (ESR1). However, our previous studies and others have observed that structural variants, such as ESR1 fusions, may also play a role. Therefore, we...

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Publicat a:Mol Cancer Res
Autors principals: Basudan, Ahmed, Priedigkeit, Nolan, Hartmaier, Ryan J, Sokol, Ethan S, Bahreini, Amir, Watters, Rebecca J, Boisen, Michelle M, Bhargava, Rohit, Weiss, Kurt R, Karsten, Maria M, Denkert, Carsten, Blohmer, Jens-Uwe, Leone, Jose P, Hamilton, Ronald L., Brufsky, Adam M, Elishaev, Esther, Lucas, Peter C., Lee, Adrian V., Oesterreich, Steffi
Format: Artigo
Idioma:Inglês
Publicat: 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6359977/
https://ncbi.nlm.nih.gov/pubmed/30355675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-18-0946
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