Corticosteroids and Methotrexate as Adjuvants to Costimulation Blockade in Nonhuman Primate Renal Transplantation

Belatacept, the CD28-B7 costimulation pathway inhibitor, has been approved as a calcineurin inhibitor (CNI) alternative in kidney transplantation. Although costimulation blockade (CoB) allows for CNI avoidance, it is associated with increased rates of early rejection, prompting a search for agents t...

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Опубликовано в: :Clin Transplant
Главные авторы: Anderson, Douglas J., Lo, Denise J., Leopardi, Francis, Song, Mingqing, Strobert, Elizabeth A., Jenkins, Joe B., Larsen, Christian P., Kirk, Allan D.
Формат: Artigo
Язык:Inglês
Опубликовано: 2019
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6597274/
https://ncbi.nlm.nih.gov/pubmed/31006146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ctr.13568
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