A mechanism for preventing asymmetric histone segregation onto replicating DNA strands

How parental histone (H3–H4)(2) tetramers, the primary carriers of epigenetic modifications, are transferred onto leading and lagging strands of DNA replication forks for epigenetic inheritance remains elusive. Here, we show that parental (H3–H4)(2) tetramers are assembled into nucleosomes onto both...

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Veröffentlicht in:Science
Hauptverfasser: Yu, Chuanhe, Gan, Haiyun, Serra-Cardona, Albert, Zhang, Lin, Gan, Songlin, Sharma, Sushma, Johansson, Erik, Chabes, Andrei, Xu, Rui-Ming, Zhang, Zhiguo
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6597248/
https://ncbi.nlm.nih.gov/pubmed/30115745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aat8849
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