A mechanism for preventing asymmetric histone segregation onto replicating DNA strands

How parental histone (H3–H4)(2) tetramers, the primary carriers of epigenetic modifications, are transferred onto leading and lagging strands of DNA replication forks for epigenetic inheritance remains elusive. Here, we show that parental (H3–H4)(2) tetramers are assembled into nucleosomes onto both...

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Detalhes bibliográficos
Publicado no:Science
Main Authors: Yu, Chuanhe, Gan, Haiyun, Serra-Cardona, Albert, Zhang, Lin, Gan, Songlin, Sharma, Sushma, Johansson, Erik, Chabes, Andrei, Xu, Rui-Ming, Zhang, Zhiguo
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6597248/
https://ncbi.nlm.nih.gov/pubmed/30115745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aat8849
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