USP16-mediated deubiquitination of calcineurin A controls peripheral T cell maintenance

Calcineurin acts as a calcium-activated phosphatase that dephosphorylates various substrates, including members of the nuclear factor of activated T cells (NFAT) family, to trigger their nuclear translocation and transcriptional activity. However, the detailed mechanism regulating the recruitment of...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Zhang, Yu, Liu, Rong-bei, Cao, Qian, Fan, Ke-qi, Huang, Ling-jie, Yu, Jian-shuai, Gao, Zheng-jun, Huang, Tao, Zhong, Jiang-yan, Mao, Xin-tao, Wang, Fei, Xiao, Peng, Zhao, Yuan, Feng, Xin-hua, Li, Yi-yuan, Jin, Jin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6597231/
https://ncbi.nlm.nih.gov/pubmed/31135381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI123801
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