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Endothelial plasminogen activator inhibitor-1 blocks the intrinsic pathway of coagulation, inducing the clearance and degradation of factor XIa.

OBJECTIVE: Activation of coagulation factor (F) XI by activated coagulation FXII (FXIIa) is a prothrombotic process. The endothelium is known to play an antithrombotic role by limiting thrombin generation and platelet activation. It is unknown whether the antithrombotic role of the endothelium inclu...

詳細記述

保存先:
書誌詳細
出版年:Arterioscler Thromb Vasc Biol
主要な著者: Puy, Cristina, Ngo, Anh T.P., Pang, Jiaqing, Keshari, Ravi S., Hagen, Matthew W., Hinds, Monica T, Gailani, David, Gruber, András, Lupu, Florea, McCarty, Owen J. T.
フォーマット: Artigo
言語:Inglês
出版事項: 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6597189/
https://ncbi.nlm.nih.gov/pubmed/31242030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.119.312619
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