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Endothelial plasminogen activator inhibitor-1 blocks the intrinsic pathway of coagulation, inducing the clearance and degradation of factor XIa.
OBJECTIVE: Activation of coagulation factor (F) XI by activated coagulation FXII (FXIIa) is a prothrombotic process. The endothelium is known to play an antithrombotic role by limiting thrombin generation and platelet activation. It is unknown whether the antithrombotic role of the endothelium inclu...
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| Pubblicato in: | Arterioscler Thromb Vasc Biol |
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| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6597189/ https://ncbi.nlm.nih.gov/pubmed/31242030 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.119.312619 |
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