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Membrane-Associated Effects of Glucocorticoid on BACE1 Upregulation and Aβ Generation: Involvement of Lipid Raft-Mediated CREB Activation

Glucocorticoid has been widely accepted to induce Alzheimer's disease, but the nongenomic effect of glucocorticoid on amyloid β (Aβ) generation has yet to be studied. Here, we investigated the effect of the nongenomic pathway induced by glucocorticoid on amyloid precursor protein processing enz...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Choi, Gee Euhn, Lee, Sei-Jung, Lee, Hyun Jik, Ko, So Hee, Chae, Chang Woo, Han, Ho Jae
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6596868/
https://ncbi.nlm.nih.gov/pubmed/28855330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0074-17.2017
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