BNIP3 induction by hypoxia stimulates FASN-dependent free fatty acid production enhancing therapeutic potential of umbilical cord blood-derived human mesenchymal stem cells

Mitophagy under hypoxia is an important factor for maintaining and regulating stem cell functions. We previously demonstrated that fatty acid synthase (FASN) induced by hypoxia is a critical lipid metabolic factor determining the therapeutic efficacy of umbilical cord blood-derived human mesenchymal...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Lee, Hyun Jik, Jung, Young Hyun, Choi, Gee Euhn, Ko, So Hee, Lee, Sei-Jung, Lee, Sang Hun, Han, Ho Jae
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5508529/
https://ncbi.nlm.nih.gov/pubmed/28704726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2017.07.004
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