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Succinate promotes stem cell migration through the GPR91-dependent regulation of DRP1-mediated mitochondrial fission

The role of metabolites produced from stem cell metabolism has been emerged as signaling molecules to regulate stem cell behaviors such as migration. The mitochondrial morphology is closely associated with the metabolic balance and stem cell function. However, the physiological role of succinate on...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Ko, So Hee, Choi, Gee Euhn, Oh, Ji Young, Lee, Hyun Jik, Kim, Jun Sung, Chae, Chang Woo, Choi, Diana, Han, Ho Jae
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5626702/
https://ncbi.nlm.nih.gov/pubmed/28974722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12692-x
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