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Succinate promotes stem cell migration through the GPR91-dependent regulation of DRP1-mediated mitochondrial fission

The role of metabolites produced from stem cell metabolism has been emerged as signaling molecules to regulate stem cell behaviors such as migration. The mitochondrial morphology is closely associated with the metabolic balance and stem cell function. However, the physiological role of succinate on...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ko, So Hee, Choi, Gee Euhn, Oh, Ji Young, Lee, Hyun Jik, Kim, Jun Sung, Chae, Chang Woo, Choi, Diana, Han, Ho Jae
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5626702/
https://ncbi.nlm.nih.gov/pubmed/28974722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12692-x
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