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Succinate induces aberrant mitochondrial fission in cardiomyocytes through GPR91 signaling
Altered mitochondrial metabolism acts as an initial cause for cardiovascular diseases and metabolic intermediate succinate emerges as a mediator of mitochondrial dysfunction. This work aims to investigate whether or not extracellular succinate accumulation and its targeted G protein-coupled receptor...
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| Publicado no: | Cell Death Dis |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5986788/ https://ncbi.nlm.nih.gov/pubmed/29867110 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0708-5 |
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