Acid-Sensing Ion Channels Activated by Evoked Released Protons Modulate Synaptic Transmission at the Mouse Calyx of Held Synapse

Acid-sensing ion channels (ASICs) regulate synaptic activities and play important roles in neurodegenerative diseases. We found that these channels can be activated in neurons of the medial nucleus of the trapezoid body (MNTB) of the auditory system in the CNS. A drop in extracellular pH induces tra...

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Udgivet i:J Neurosci
Main Authors: González-Inchauspe, Carlota, Urbano, Francisco J., Di Guilmi, Mariano N., Uchitel, Osvaldo D.
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2017
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6596635/
https://ncbi.nlm.nih.gov/pubmed/28159907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2566-16.2017
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