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Acid-Sensing Ion Channels Activated by Evoked Released Protons Modulate Synaptic Transmission at the Mouse Calyx of Held Synapse

Acid-sensing ion channels (ASICs) regulate synaptic activities and play important roles in neurodegenerative diseases. We found that these channels can be activated in neurons of the medial nucleus of the trapezoid body (MNTB) of the auditory system in the CNS. A drop in extracellular pH induces tra...

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Dettagli Bibliografici
Pubblicato in:J Neurosci
Autori principali: González-Inchauspe, Carlota, Urbano, Francisco J., Di Guilmi, Mariano N., Uchitel, Osvaldo D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6596635/
https://ncbi.nlm.nih.gov/pubmed/28159907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2566-16.2017
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