Presynaptic Ca(V)2.1 calcium channels carrying familial hemiplegic migraine mutation R192Q allow faster recovery from synaptic depression in mouse calyx of Held

Ca(V)2.1 Ca(2+) channels have a dominant and specific role in initiating fast synaptic transmission at central excitatory synapses, through a close association between release sites and calcium sensors. Familial hemiplegic migraine type 1 (FHM-1) is an autosomal-dominant subtype of migraine with aur...

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Hlavní autoři: Inchauspe, Carlota González, Urbano, Francisco J., Di Guilmi, Mariano N., Ferrari, Michel D., van den Maagdenberg, Arn M. J. M., Forsythe, Ian D., Uchitel, Osvaldo D.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3544873/
https://ncbi.nlm.nih.gov/pubmed/22956801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.01183.2011
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